How Eli Lilly's biotech collaboration model is rewriting early-stage innovation
Fri Feb 06 2026
Today, we're joined by Thomas Hopkins, Vice President and Head of ExploR&D at Eli Lilly. With a background as a physician-scientist in oncology, Thomas has spent his career bridging bold discovery science with rigorous development, first in academia and clinical practice, then at Lilly since 2015.
Lilly ExploR&D represents new thinking in the pharma-biotech collaboration model: a shared-risk, deep scientific partnership designed specifically for early-stage biotechs. It provides full-stack R&D capabilities helping companies overcome the toughest hurdles in moving from molecule creation to clinical proof-of-concept, all while staying lean in a challenging funding environment.
In this episode, Thomas dives into his journey shaping ExploR&D, how the program works in practice, current priorities in modalities and therapeutic areas, and offers some practical advice for biotechs seeking to partner with Eli Lilly.
01:30 — Meet Tom Hopkins
05:11 — What makes ExploR&D biotech-friendly
07:46 — How collaborations work in practice
09:40 — Shared risk models
14:25 — Engaging bold science early
28:16 — Success stories and advice for biotechs
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To dive deeper into the topic:
Eli Lilly’s strategy in motion: Beyond diabetes and obesityOver $3 billion in a month: Why is Eli Lilly starting 2025 on a buying spree?What to look for in a biotech incubator
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Today, we're joined by Thomas Hopkins, Vice President and Head of ExploR&D at Eli Lilly. With a background as a physician-scientist in oncology, Thomas has spent his career bridging bold discovery science with rigorous development, first in academia and clinical practice, then at Lilly since 2015. Lilly ExploR&D represents new thinking in the pharma-biotech collaboration model: a shared-risk, deep scientific partnership designed specifically for early-stage biotechs. It provides full-stack R&D capabilities helping companies overcome the toughest hurdles in moving from molecule creation to clinical proof-of-concept, all while staying lean in a challenging funding environment. In this episode, Thomas dives into his journey shaping ExploR&D, how the program works in practice, current priorities in modalities and therapeutic areas, and offers some practical advice for biotechs seeking to partner with Eli Lilly. 01:30 — Meet Tom Hopkins 05:11 — What makes ExploR&D biotech-friendly 07:46 — How collaborations work in practice 09:40 — Shared risk models 14:25 — Engaging bold science early 28:16 — Success stories and advice for biotechs Interested in being a sponsor of an episode of our podcast? Discover how you can get involved here! Stay updated by subscribing to our newsletter To dive deeper into the topic: Eli Lilly’s strategy in motion: Beyond diabetes and obesityOver $3 billion in a month: Why is Eli Lilly starting 2025 on a buying spree?What to look for in a biotech incubator