Compounding Pharmacies: Purity, Testing & Personalized Medicine with Dr. Leonard Pastrana and Dr. Frank Kacou
Thu Jan 15 2026
In this episode, Elizabeth Tringal, PA-Ci is joined by Dr. Leonard Pastrana and Dr. Frank Kacou, founders of NubioAge and NuHX, to go deep into what truly separates exceptional compounding pharmacies from the rest.
They break down how compounded therapies support personalization in ways conventional pharmaceuticals can’t, from micro-dosing GLP-1s to creating cleaner hormone formulas, mitochondrial peptides, and nasal therapies that dramatically improve absorption. The conversation dives into why testing standards matter, how pharmaceutical-grade vs food-grade ingredients change outcomes, and why waiting on backorders often means your pharmacy is doing things right.
A major focus is long COVID and the accelerated aging providers are seeing: brain fog, immune dysfunction, fatigue, kidney stress, and metabolic decline. Leonard and Frank explain why most protocols start with the gut, how spike protein may be hiding in the microbiome, and why mitochondrial repair is central to recovery. They discuss stacks involving peptides, methylene blue, NAD, tryptophan, butyrate, and gut-supportive compounds that clinicians are using right now.
You’ll also hear:
Why nasal delivery can outperform oral dosing for certain therapiesHow methylene blue supports mitochondrial energy and cognitive clarityThe difference between hydration and true cellular hydrationWhat “mitochondrial flexibility” means and how it’s measuredWhy exercise tolerance is one of the strongest markers of brain recoveryHow dosing errors derail otherwise perfect protocolsWhy compounding allows medicine to meet the patient, not the other way aroundThis episode is a masterclass in how functional medicine, pharmacy, and longevity science intersect—and why compounding is not something to fear, but something to understand deeply and use intelligently.
Links:
Nubioage: a longevity science and wellness education network serving medical practitioners and allied health professionals focused on delivering patient-centric, evidence-based longevity medicine.NuHX: Advanced, comprehensive metrics and health data analysis.Products Mentioned:
Icell WaterSytrinol LNAAKGPeptides at Tringali Vibrant HealthTringali Vibrant Health Website
Tringali Vibrant Health Online Supplement Store
More
In this episode, Elizabeth Tringal, PA-Ci is joined by Dr. Leonard Pastrana and Dr. Frank Kacou, founders of NubioAge and NuHX, to go deep into what truly separates exceptional compounding pharmacies from the rest. They break down how compounded therapies support personalization in ways conventional pharmaceuticals can’t, from micro-dosing GLP-1s to creating cleaner hormone formulas, mitochondrial peptides, and nasal therapies that dramatically improve absorption. The conversation dives into why testing standards matter, how pharmaceutical-grade vs food-grade ingredients change outcomes, and why waiting on backorders often means your pharmacy is doing things right. A major focus is long COVID and the accelerated aging providers are seeing: brain fog, immune dysfunction, fatigue, kidney stress, and metabolic decline. Leonard and Frank explain why most protocols start with the gut, how spike protein may be hiding in the microbiome, and why mitochondrial repair is central to recovery. They discuss stacks involving peptides, methylene blue, NAD, tryptophan, butyrate, and gut-supportive compounds that clinicians are using right now. You’ll also hear: Why nasal delivery can outperform oral dosing for certain therapiesHow methylene blue supports mitochondrial energy and cognitive clarityThe difference between hydration and true cellular hydrationWhat “mitochondrial flexibility” means and how it’s measuredWhy exercise tolerance is one of the strongest markers of brain recoveryHow dosing errors derail otherwise perfect protocolsWhy compounding allows medicine to meet the patient, not the other way aroundThis episode is a masterclass in how functional medicine, pharmacy, and longevity science intersect—and why compounding is not something to fear, but something to understand deeply and use intelligently. Links: Nubioage: a longevity science and wellness education network serving medical practitioners and allied health professionals focused on delivering patient-centric, evidence-based longevity medicine.NuHX: Advanced, comprehensive metrics and health data analysis.Products Mentioned: Icell WaterSytrinol LNAAKGPeptides at Tringali Vibrant HealthTringali Vibrant Health Website Tringali Vibrant Health Online Supplement Store