Quantified Longevity: Biohacking To Extend Healthspan | Ryan Cabeen PhD, x-CTO at Blueprint (Longevity Series)
Tue Feb 03 2026
Can we measure our way to a longer, healthier life?
In this episode of The Health Curve, I sit down with Ryan Cabeen, PhD — former CTO at Blueprint and biomedical AI researcher — to unpack the world of quantified longevity: data, wearables, biomarkers, and what actually moves the needle for health and lifespan.
We talk about the rise of the quantified self movement, how consumer tech has transformed what we can track (sleep, steps, heart rate, biomarkers and more), and where the science is solid vs still experimental. Ryan explains the difference between top-down “live better now” strategies (sleep, diet, movement, stress) and bottom-up molecular longevity approaches (gene therapy, cellular reprogramming, stem cells, rapamycin, GLP-1s).
We also get into the ethics and realities of longevity clinics, “over-measurement,” animal studies that haven’t yet translated to humans, and emerging tools like digital twins that could one day simulate our future health. Finally, Ryan shares what he thinks people are really seeking when they chase longevity.
If you’re curious about longevity, biohacking, Blueprint, or quantified self, but want a grounded, evidence-aware conversation, this one’s for you.
👉 If you find this helpful, please subscribe to The Health Curve, and share it with someone who’s curious about longevity or health optimization.
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Can we measure our way to a longer, healthier life? In this episode of The Health Curve, I sit down with Ryan Cabeen, PhD — former CTO at Blueprint and biomedical AI researcher — to unpack the world of quantified longevity: data, wearables, biomarkers, and what actually moves the needle for health and lifespan. We talk about the rise of the quantified self movement, how consumer tech has transformed what we can track (sleep, steps, heart rate, biomarkers and more), and where the science is solid vs still experimental. Ryan explains the difference between top-down “live better now” strategies (sleep, diet, movement, stress) and bottom-up molecular longevity approaches (gene therapy, cellular reprogramming, stem cells, rapamycin, GLP-1s). We also get into the ethics and realities of longevity clinics, “over-measurement,” animal studies that haven’t yet translated to humans, and emerging tools like digital twins that could one day simulate our future health. Finally, Ryan shares what he thinks people are really seeking when they chase longevity. If you’re curious about longevity, biohacking, Blueprint, or quantified self, but want a grounded, evidence-aware conversation, this one’s for you. 👉 If you find this helpful, please subscribe to The Health Curve, and share it with someone who’s curious about longevity or health optimization.