Tesamorelin vs CJC1295: What's Better with Ipamorelin?
Wed Dec 31 2025
In this episode, Jeff & Blake break down one of the most common peptide questions they hear from patients right now: whether Tesamorelin or CJC-1295 with Ipamorelin is the better option depending on specific goals. Drawing directly from real-world clinic experience, they explain how each peptide works in the body, how growth hormone pulses differ between nighttime and morning use, and why sleep quality, recovery, and body composition outcomes can vary so widely from person to person. The discussion also addresses visceral fat reduction, REM and deep sleep improvements, histamine-type reactions some patients experience, and why stacking certain peptides can deliver more consistent results when done correctly. Throughout the conversation, Jeff & Blake emphasize the importance of bloodwork, medically supervised dosing, and avoiding “research-only” products in favor of properly compounded peptides from licensed pharmacies.
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The ManLab is a podcast focused on Making Men Great Again, sharing practical conversations around men’s physical health, mental performance, and long-term optimization.
The ManLab is sponsored by T-Clinics USA, a men’s medical health clinic providing Testosterone, Peptides, and other therapies designed to support safe, compliant, and effective treatment.
The ManLab is produced by SKY MEDIA HOUSE 👉 https://www.skymediahouse.com
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In this episode, Jeff & Blake break down one of the most common peptide questions they hear from patients right now: whether Tesamorelin or CJC-1295 with Ipamorelin is the better option depending on specific goals. Drawing directly from real-world clinic experience, they explain how each peptide works in the body, how growth hormone pulses differ between nighttime and morning use, and why sleep quality, recovery, and body composition outcomes can vary so widely from person to person. The discussion also addresses visceral fat reduction, REM and deep sleep improvements, histamine-type reactions some patients experience, and why stacking certain peptides can deliver more consistent results when done correctly. Throughout the conversation, Jeff & Blake emphasize the importance of bloodwork, medically supervised dosing, and avoiding “research-only” products in favor of properly compounded peptides from licensed pharmacies. =================== 🚨Receive 10% off Your First Purchase with T-Clinics ▶ https://bit.ly/TclinicsUSA Take your Free ADAM Test ▶ https://bit.ly/freeadamtest The ManLab is a podcast focused on Making Men Great Again, sharing practical conversations around men’s physical health, mental performance, and long-term optimization. The ManLab is sponsored by T-Clinics USA, a men’s medical health clinic providing Testosterone, Peptides, and other therapies designed to support safe, compliant, and effective treatment. The ManLab is produced by SKY MEDIA HOUSE 👉 https://www.skymediahouse.com