5 Subtle Signs Your Kidneys May Be Failing (Most People Miss These)
Thu Feb 05 2026
In this episode of Wellness Focused, I walk through five subtle warning signs that your kidneys may be struggling long before you feel seriously ill—and why these signals are so often overlooked or dismissed.
After years of clinical practice, I’ve seen how frequently patients lose significant kidney function before anyone realizes what’s happening. In fact, it’s possible to lose up to 70% of kidney function before obvious symptoms appear. What makes this so concerning is that the early signs are usually present—but subtle, easy to normalize, and rarely connected back to kidney health.
I explain how changes like persistent foamy urine, unexplained swelling, deep fatigue that sleep doesn’t fix, shifts in urination patterns, and chronic itching can reflect underlying kidney stress. I also break down the physiology behind these symptoms, including how protein leakage damages kidney filters, how declining kidney function contributes to anemia and fatigue, and why nighttime urination can be an early red flag.
We also discuss why these signs are frequently attributed to aging, stress, or unrelated conditions—and how that delay in recognition can cost patients valuable time. This episode emphasizes why early investigation, comprehensive kidney testing, and self-advocacy can dramatically change outcomes.
This episode is meant to help patients and clinicians recognize that the body is always communicating—and that paying attention early can help protect kidney function before irreversible damage occurs.
I’m Dr. Bismah Irfan, MD, a board-certified nephrologist and functional medicine physician. I help patients with kidney disease and complex immune conditions navigate personalized, evidence-based strategies to protect long-term health and avoid preventable complications.
Bismah Irfan, MD
Facebook: https://www.facebook.com/KidneyHealthMD
Instagram: https://www.instagram.com/kidney.healthmd/
LinkedIn: https://www.linkedin.com/in/drbismah/
Website: https://www.drbismah.com/about/
Produced by DrTalks
https://drtalks.com/podcast-service/
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In this episode of Wellness Focused, I walk through five subtle warning signs that your kidneys may be struggling long before you feel seriously ill—and why these signals are so often overlooked or dismissed. After years of clinical practice, I’ve seen how frequently patients lose significant kidney function before anyone realizes what’s happening. In fact, it’s possible to lose up to 70% of kidney function before obvious symptoms appear. What makes this so concerning is that the early signs are usually present—but subtle, easy to normalize, and rarely connected back to kidney health. I explain how changes like persistent foamy urine, unexplained swelling, deep fatigue that sleep doesn’t fix, shifts in urination patterns, and chronic itching can reflect underlying kidney stress. I also break down the physiology behind these symptoms, including how protein leakage damages kidney filters, how declining kidney function contributes to anemia and fatigue, and why nighttime urination can be an early red flag. We also discuss why these signs are frequently attributed to aging, stress, or unrelated conditions—and how that delay in recognition can cost patients valuable time. This episode emphasizes why early investigation, comprehensive kidney testing, and self-advocacy can dramatically change outcomes. This episode is meant to help patients and clinicians recognize that the body is always communicating—and that paying attention early can help protect kidney function before irreversible damage occurs. I’m Dr. Bismah Irfan, MD, a board-certified nephrologist and functional medicine physician. I help patients with kidney disease and complex immune conditions navigate personalized, evidence-based strategies to protect long-term health and avoid preventable complications. Bismah Irfan, MD Facebook: https://www.facebook.com/KidneyHealthMD Instagram: https://www.instagram.com/kidney.healthmd/ LinkedIn: https://www.linkedin.com/in/drbismah/ Website: https://www.drbismah.com/about/ Produced by DrTalks https://drtalks.com/podcast-service/