How OpenAI Is Helping People Take Control of Their Health | Fidji Simo
Wed Feb 04 2026
Too often, we focus on treating symptoms without fully understanding the systems underneath them—or the conditions that allow the body to function well in the first place.
On this episode of The Dr. Hyman Show, I sit down with Fidji Simo, CEO of Applications at OpenAI, to explore how AI could help us shift medicine from treating symptoms to restoring systems. We talk about why chronic illness is so often misunderstood, how health data has been fragmented across silos, and what becomes possible when we finally see the full picture. Watch the full conversation on YouTube or listen wherever you get your podcasts.
In this episode, you’ll learn:
• Why having a diagnosis doesn’t always explain what’s actually driving your symptoms
• How connecting your labs, lifestyle data, and health history can reveal patterns you might otherwise miss
• What it looks like to move from reactive care to proactive, personalized health
• How better context can help you make clearer decisions about food, sleep, movement, and recovery
Health isn’t built in a doctor’s office. When you create the right environment, the body often knows what to do—and understanding your own biology is one of the most powerful steps you can take toward creating health, not just reacting to disease.
View Show Notes From This Episode
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This episode is brought to you by Sunlighten, Paleovalley, PerfectAmino, Seed, Made In Cookware and Fatty15.
Visit sunlighten.com and use code HYMAN to save up to $1400.
Head to paleovalley.com and use code HYMAN20 for 20% off your first order.
Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order.
Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month.
Head to madeincookware.com and use the code DRHYMAN for 10% off your order.
Visit fatty15.com/hyman and use code HYMAN to save an extra 15% on a 90-day subscription.
(0:00) Introduction
(1:27) Dr. Hyman on the revolutionary potential of ChatGPT Health and the complexity of the body
(3:29) Fidji Simo's health journey, challenges in chronic illness, and health system shortcomings
(7:42) The role of AI in health care: Empowerment, personalized medicine, and practical applications
(20:24) OpenAI's focus on health applications and preventative health with CHATGPT
(23:16) True prevention, creating health, and nutrition action through partnerships
(29:08) Cultural differences in food, health, and empowering consumers with AI
(33:44) AI's role in drug discovery, curing diseases, and democratizing health information
(43:12) Chronicle Bio's mission and impact
(52:27) Challenges and opportunities at the intersection of health and technology
(56:07) Future goals and three key areas of impact for ChatGPT Health
(1:00:52) Food system design and its impact on health
(1:02:00) Closing remarks
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Too often, we focus on treating symptoms without fully understanding the systems underneath them—or the conditions that allow the body to function well in the first place. On this episode of The Dr. Hyman Show, I sit down with Fidji Simo, CEO of Applications at OpenAI, to explore how AI could help us shift medicine from treating symptoms to restoring systems. We talk about why chronic illness is so often misunderstood, how health data has been fragmented across silos, and what becomes possible when we finally see the full picture. Watch the full conversation on YouTube or listen wherever you get your podcasts. In this episode, you’ll learn: • Why having a diagnosis doesn’t always explain what’s actually driving your symptoms • How connecting your labs, lifestyle data, and health history can reveal patterns you might otherwise miss • What it looks like to move from reactive care to proactive, personalized health • How better context can help you make clearer decisions about food, sleep, movement, and recovery Health isn’t built in a doctor’s office. When you create the right environment, the body often knows what to do—and understanding your own biology is one of the most powerful steps you can take toward creating health, not just reacting to disease. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Sunlighten, Paleovalley, PerfectAmino, Seed, Made In Cookware and Fatty15. Visit sunlighten.com and use code HYMAN to save up to $1400. Head to paleovalley.com and use code HYMAN20 for 20% off your first order. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month. Head to madeincookware.com and use the code DRHYMAN for 10% off your order. Visit fatty15.com/hyman and use code HYMAN to save an extra 15% on a 90-day subscription. (0:00) Introduction (1:27) Dr. Hyman on the revolutionary potential of ChatGPT Health and the complexity of the body (3:29) Fidji Simo's health journey, challenges in chronic illness, and health system shortcomings (7:42) The role of AI in health care: Empowerment, personalized medicine, and practical applications (20:24) OpenAI's focus on health applications and preventative health with CHATGPT (23:16) True prevention, creating health, and nutrition action through partnerships (29:08) Cultural differences in food, health, and empowering consumers with AI (33:44) AI's role in drug discovery, curing diseases, and democratizing health information (43:12) Chronicle Bio's mission and impact (52:27) Challenges and opportunities at the intersection of health and technology (56:07) Future goals and three key areas of impact for ChatGPT Health (1:00:52) Food system design and its impact on health (1:02:00) Closing remarks