Dr. Chris Masterjohn, PhD - Mitochondria, Micronutrients, and How Nutrition Actually Drives Longevity
Thu Feb 05 2026
When cellular energy production is impaired, no diet, supplement, or health protocol can work as intended.
In this episode, Dr. Chris Masterjohn, nutrition scientist and expert in micronutrients and metabolism, explains why mitochondrial function is the limiting factor behind stalled progress, persistent fatigue, and supplements that stop working over time.
He breaks down why vitamin D supplementation often creates new problems when it is taken without proper nutrient balance, how high doses can disrupt other systems in the body, and why sunlight has biological effects that vitamin D pills alone cannot replicate.
Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/checkout/become-a-member
This conversation explores:
Why mitochondrial bottlenecks explain most energy and health plateaus
How micronutrient deficiencies undermine supplements and biohacks
When creatine supports cellular energy and why it works differently than most supplements
Why vitamin D supplementation can backfire without context and balance
Why sunlight affects biology in ways supplements cannot replace
How diet, fasting, and exercise interact with mitochondrial capacity
Why optimizing one system often breaks another without proper foundations
Connect with Kayla:
Instagram: https://www.instagram.com/kaylabarnes/
TikTok: https://www.tiktok.com/@femalelongevity
Twitter:https://x.com/femalelongevity
Website:https://www.kaylabarnes.com/
Spotify:https://open.spotify.com/show/4OLWWn22...
Apple: https://podcasts.apple.com/us/podcast...
Follow Her Female Protocol: https://www.protocol.kaylabarnes.comLearn more about Dr Chris Masterjohn’s work:
Website: https://www.chrismasterjohn-phd.com/Instagram: https://www.instagram.com/chrismasterjohn/YouTube: https://www.youtube.com/@chrismasterjohn
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When cellular energy production is impaired, no diet, supplement, or health protocol can work as intended. In this episode, Dr. Chris Masterjohn, nutrition scientist and expert in micronutrients and metabolism, explains why mitochondrial function is the limiting factor behind stalled progress, persistent fatigue, and supplements that stop working over time. He breaks down why vitamin D supplementation often creates new problems when it is taken without proper nutrient balance, how high doses can disrupt other systems in the body, and why sunlight has biological effects that vitamin D pills alone cannot replicate. Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/checkout/become-a-member This conversation explores: Why mitochondrial bottlenecks explain most energy and health plateaus How micronutrient deficiencies undermine supplements and biohacks When creatine supports cellular energy and why it works differently than most supplements Why vitamin D supplementation can backfire without context and balance Why sunlight affects biology in ways supplements cannot replace How diet, fasting, and exercise interact with mitochondrial capacity Why optimizing one system often breaks another without proper foundations Connect with Kayla: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter:https://x.com/femalelongevity Website:https://www.kaylabarnes.com/ Spotify:https://open.spotify.com/show/4OLWWn22... Apple: https://podcasts.apple.com/us/podcast... Follow Her Female Protocol: https://www.protocol.kaylabarnes.comLearn more about Dr Chris Masterjohn’s work: Website: https://www.chrismasterjohn-phd.com/Instagram: https://www.instagram.com/chrismasterjohn/YouTube: https://www.youtube.com/@chrismasterjohn