How Methylation and Genetics Affect Mental Health | Episode 74 with Towny Robinson
Mon Feb 02 2026
Towny Robinson, CEO of JayMac Pharmaceuticals and inventor of EnLyte, joins us to break down the science of methylation and why it plays such a critical role in mental health, brain development, and overall wellness. We dig into how the brain uses nutrients, especially B vitamins, to produce neurotransmitters like serotonin, dopamine, and GABA, and why disruptions in this process can show up as depression, anxiety, ADHD, bipolar disorder, addiction, and more. Towny explains how genetic polymorphisms (including but not limited to MTHFR) and environmental factors can impair methylation, leading to what many people experience as a “chemical imbalance.”
We also explore cerebral folate deficiency, autism, PANS/PANDAS, and other neurodevelopmental conditions, including how autoimmune blocks can prevent folate from reaching the brain and what forms of folate can safely bypass those pathways. Together, we unpack why single-nutrient supplementation often falls short, the importance of a full-spectrum, coenzyme-based approach, and how EnLyte was designed to support methylation at multiple points in the pathway. This conversation reframes mental health symptoms by focusing on root causes and offers a hopeful, science-backed explanation for how balance and normalization are possible.
If you’re interested in learning more about Towny’s work, you can visit EnLyte's website, https://www.enlyterx.com/ , for additional information and resources.
Join Dr. Lauren LaRose, psychiatrist and mom of three, as she brings on experts in mental health, physical health and education and explores ideas outside the traditional medical model. The Little Brain Campaign aims to make issues kids and caregivers face easier to understand, while always keeping in mind that we need to look beyond the usual answers to find what really works.
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Towny Robinson, CEO of JayMac Pharmaceuticals and inventor of EnLyte, joins us to break down the science of methylation and why it plays such a critical role in mental health, brain development, and overall wellness. We dig into how the brain uses nutrients, especially B vitamins, to produce neurotransmitters like serotonin, dopamine, and GABA, and why disruptions in this process can show up as depression, anxiety, ADHD, bipolar disorder, addiction, and more. Towny explains how genetic polymorphisms (including but not limited to MTHFR) and environmental factors can impair methylation, leading to what many people experience as a “chemical imbalance.” We also explore cerebral folate deficiency, autism, PANS/PANDAS, and other neurodevelopmental conditions, including how autoimmune blocks can prevent folate from reaching the brain and what forms of folate can safely bypass those pathways. Together, we unpack why single-nutrient supplementation often falls short, the importance of a full-spectrum, coenzyme-based approach, and how EnLyte was designed to support methylation at multiple points in the pathway. This conversation reframes mental health symptoms by focusing on root causes and offers a hopeful, science-backed explanation for how balance and normalization are possible. If you’re interested in learning more about Towny’s work, you can visit EnLyte's website, https://www.enlyterx.com/ , for additional information and resources. Join Dr. Lauren LaRose, psychiatrist and mom of three, as she brings on experts in mental health, physical health and education and explores ideas outside the traditional medical model. The Little Brain Campaign aims to make issues kids and caregivers face easier to understand, while always keeping in mind that we need to look beyond the usual answers to find what really works. Follow The Little Brain Campaign Instagram: https://www.instagram.com/littlebraincampaign